"The work has the potential to transform how we estimate disease risk in clinical practice." - Iftikhar Kullo, M.D.ĭollars from the award will be used to build upon the Electronic Medical Records and Genomics (eMERGE) Network, a consortium of medical research organizations, to fund a coordinating center and clinical sites. part of $75 million in funding over five years to improve the role of genomics in assessing and managing disease risk. In his laboratory, he intensively studies the Genetics of arterial plaques (atherosclerosis), Familial hypercholesterolemia (FH), and Implements genomic medicine in the EHR, Genomic discovery using EHRs, Proteomic markers for vascular disease, Arterial stiffness, and ventricular arterial interactions, Peripheral arterial disease (PAD), and Vascular diseases biorepository.In recognition of their high impact work of advancing the field of genetic risk profiling for disease risk stratification, the National Institutes of Health (NIH) has awarded Mayo Clinic researchers Iftikhar Kullo, M.D. Dr Kullo’s laboratory emphasizes the improvement of the facility to predict adverse cardiovascular events in asymptomatic individuals using genetic susceptibility markers, circulating biomarkers, and measurements of arterial function. These include genetic markers, circulating biomarkers, and noninvasive tests of arterial function and structure. Utilizing his Atherosclerosis and Lipid Genomics Laboratory, Dr Kullo investigates the use of new methodologies in refining cardiovascular risk stratification. Dr Kullo investigates the use of new methodologies in refining cardiovascular risk stratification. The major focus of his research is the genetic basis of Coronary Heart Disease, the implementation of Genomic Medicine, and the biomarkers of cardiovascular risk. Genomics is transforming biomedical research and I’m excited to have the opportunity to advise on the discovery and implementation aspects of genomic medicine to improve outcomes for our patients,” Dr Kullo has said after his appointment to the National Advisory Council on Human Genome Research. “I am honoured to serve on the National Advisory Council on Human Genome Research. He, later, joined as Clinician-Investigator Program and fellow at Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine. Subsequently, Dr Kullo remained as a Resident in Internal Medicine at Mayo School of Graduate Medical Education. He did his internship in Internal Medicine at Nassau County Medical Center, State University of New York. Formerly, he has been a Resident of Internal Medicine, Postgraduate Institute of Medical Education and Research, and Chief Resident at Institute of Medical Sciences, Srinagar. He is a Principal Investigator in the NHGRI’s eMERGE and PRIMED consortia.ĭr Kullo has done his MBBS in the Government Medical College, Srinagar in 1987. Another project is investigating the clinical utility of a genetic risk score composed of susceptibility variants for abdominal aortic aneurysms.ĭr Kullo has incessantly been funded by the NIH (National Institutes of Health) since 2003. Besides, his laboratory conducts clinical trials in genomic medicine, such as the recently concluded Myocardial Infarction Genes (MI-GENES) study, which assessed the effect on LDL cholesterol of disclosing a genetic risk score for coronary heart disease based on 28 susceptibility variants. His focus area, according to the Mayo College website, includes the genetics of arterial plaques in which Dr Kullo’s lab uses family history studies, linkage studies, candidate gene association studies, genome-wide association studies and genome sequencing to study the genetic basis of atherosclerosis. Through his Atherosclerosis and Lipid Genomics Laboratory, Dr Kullo is investigating the use of new methodologies in refining cardiovascular risk stratification.
He is the head of the Atherosclerosis and Lipid economics Laboratory and a chairperson of the Cardiovascular Genomics Task Force. Dr Iftikhar Kullo serves as a Professor of Medicine and Science, and a Consultant in the Department of Cardiovascular Medicine and the Gonda Vascular Center at Mayo Clinic College of Medicine, Rochester, Minnesota.
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